Archive for the ‘Mevacor’ Category

Mevacor.

Tuesday, September 25th, 2007

Mevacor is used, along with diet, to lower cholesterol levels in people with primary hypercholesterolemia (too much cholesterol in the bloodstream). High cholesterol levels foster the buildup of artery-clogging plaque, which can be especially dangerous when it collects in the vessels serving the muscles of the heart. Mevacor is prescribed to prevent this problem–called coronary heart disease–or to slow its advance if the arteries are already clogging up.

Mevacor is usually prescribed only if diet, exercise, and weight-loss fail to bring your cholesterol levels under control. It’s important to remember that Mevacor is a supplement–not a substitute–for these other measures. To get the full benefit of the medication, you need to stick to the diet and exercise program prescribed by your doctor.

 

Mevacor should be taken with meals. –If you miss a dose… Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time. –Storage instructions… Protect Mevacor from light. Store at room temperature. Keep container tightly closed.

Mevacor is generally well tolerated. Any side effects that have occurred have usually been mild and short-lived. If any side effects develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Mevacor. Side effects may include: Abdominal pain/cramps, altered sense of taste, blurred vision, constipation, diarrhea, dizziness, gas, headache, heartburn, indigestion, itching, muscle cramps, muscle pain, muscle weakness with rash, nausea, rash, weakness

If you are sensitive to or have ever had an allergic reaction to Mevacor or similar anticholesterol drugs, you should not take this medication. Make sure that your doctor is aware of any drug reactions that you have experienced. Unless you are directed to do so by your doctor, do not take this medication if you are being treated for liver disease. Do not take this drug if you are pregnant or nursing.

If you are being treated for any disease that contributes to increased blood cholesterol, such as hypothyroidism, diabetes, nephrotic syndrome (kidney and blood vessel disorder), dysproteinemia (an excess of protein in the blood), or liver disease, your doctor will closely monitor your reaction to Mevacor. It is recommended that liver function tests be performed by your doctor before treatment with Mevacor begins, at 6 and 12 weeks after your treatment has started or your dosage has been raised, and periodically (about 6-month intervals) thereafter. If you are planning to have elective surgery, Mevacor should be discontinued a few days before the operation. This drug should be used with caution if you consume substantial quantities of alcohol or have a past history of liver disease.

Mevacor tends to enhance the blood-thinning effect of Coumadin. In rare instances, it can also cause muscle pain and potential kidney damage when combined with the following: Clarithromycin (Biaxin) Clofibrate (Atromid-S) Cyclosporine (Sandimmune, Neoral) Erythromycin (E.E.S., PCE, others) Fenofibrate (Tricor) Fluconazole (DiFlucan) Gemfibrozil (Lopid) Itraconazole (Sporanox) Ketoconazole (Nizoral) Nefazodone (Serzone) Nicotinic acid or niacin (Niaspan) Protease inhibitors (a type of drug for HIV) such as Agenerase, Crixivan, Fortovase, Invirase, Norvir, and Viracept If you are taking Mevacor with any of these drugs, (or with large quantities of grapefruit juice), alert your doctor immediately at the first sign of muscle pain, tenderness, or weakness, especially if accompanied by fever or general body discomfort. If you need to take erythromycin, Biaxin, Nizoral, or Sporanox, the doctor may temporarily take you off Mevacor.